Combining technology with translational science to deliver cutting-edge patient care
At Stanford, we are positioned to deliver the best possible care to children and adults using minimally invasive image-guided approaches to enable both Precision Sampling as well as Precision Delivery. Specifically, at LPCH we have state-of-the-art interventional facilities unlike any other place in the world which helps us to bring innovation directly to children so they can receive the best possible treatment. The interventional radiology team at LPCH has a progressive and pioneering culture where advanced technologies are combined with innovative approaches for both routine patient care as well as new clinical trials.
Our Team. At LPCH, Dr Thakor helps to lead an amazing team that delivers the most advanced and progressive interventional care to children through all their stages of development from birth to adulthood. Our Interventional Radiology team is supported by strong hospital leadership and a core of nurses, technologists, and advanced practitioners. In addition, we also train the next generation of physicians and healthcare providers so they can benefit from the lessons we have learned and the techniques and technologies we have developed; this way we can help to disseminate our knowledge to help all children who need medical care across the country and world.
Advanced Technologies Interventional Radiologists are at the cutting-edge interface of medical innovation and can integrate multiple imaging modalities with advanced technologies to deliver minimally invasive care for patients. These technologies include imaging equipment (i.e. fluoroscopic machines which use x-rays, ultrasound machines that use soundwaves), machines that can cause focal tissue destruction (i.e. radiofrequency ablation, cryoablation, microwave ablation, soundwave/HIFU ablation), equipment that can be deployed in blood vessels and luminal structures (i.e. particles, coils, filters, stents) and software programs that help guide interventions (i.e. fusion software for target localization or vessel mapping software for target vessel selection).
Innovative Techniques Dr Thakor and the Interventional Radiology team at LPCH are pushing forward the boundaries of how to treat children using minimally invasive high-end techniques. Examples include percutaneous reconstruction of the biliary system, percutaneous lymphatic intervention and the local delivery of medications through blood vessels into organs such as the liver, kidney and bowel as well as tumors. In addition, we are able to cause the local destruction of tumors using percutaneous thermal or endovascular tumor blocking techniques, or more recently using completely non-invasive ways via soundwaves (i.e. HIFU).
Pioneering Care The Interventional Radiology team provides essential services that are integrated into the care pathway of children in almost all other service lines. As such we offer emergency care (i.e. to the emergency department, neonatal intensive care unit, pediatric intensive care unit), urgent care (i.e. to transplant, hematology-oncology, cardiology and gastroenterology teams), and routine elective care (i.e. to dermatology, neurology, rheumatology, ENT and endocrinology teams). We work closely with our anesthesiology colleagues to provide 24/7 care, all year round, for children from the time they are born, when they can be small as 500g, all the way through to when they become adults. Our goal is to provide the highest quality care to children using minimally invasive techniques that help to support the physical and mental wellbeing of a child and family throughout their journey through our healthcare system.
Clinical Trials Dr Thakor is leading multiple efforts to bring the latest innovative approaches and technologies to the patient’s bedside. As such, he is actively involved in multiple clinical trials; some of these efforts have resulted in patients already being treated (i.e. high intensity focused ultrasound (HIFU) of bone tumors) while others (i.e. islet transplantation for children and adults, local delivery of medication into the bowel of children with IBD or GvHD) are being submitted for approval and subsequent patient recruitment. His vision is to bring the promise of MSCs and MSC-EVs, which are showing considerable promise in the laboratory, to children and adults by being able to locally deliver these therapies in different diseases including diabetes, kidney injury, liver injury and organ rejection.